• Collaborating departments:
1- Basic scientists from different departments (including immunology and biochemistry) are engaged in fundamental research on the immune response study, the causes and mechanisms of immune system dysregulation leading to autoimmune diseases. The other goal is identifying auto-antigens which are targeted by the immune system in order to develop new diagnostic and immunotherapeutical modalities for autoimmune diseases. Furthermore, they are seeking out the genetic traits that increase the risk of developing an autoimmune disease.
2- Clinicians from different clinical departments (Rheumatology, Neurology, Dermatology and Ophthalmology) are searching for methods to improve the diagnosis and treatment of related autoimmune diseases. Moreover, they are actively engaged in preparing the databanks for autoimmune diseases.
• Research areas and projects:
 1- Developing database for different autoimmune diseases including:
        a) Rheumatologic diseases:
             - Systemic Lupus Erythematosus (SLE)
             - Rheumatoid Arthritis (RA)
             - Scleroderma
             - Behcet
        b) Neurological diseases:
             - Multiple Sclerosis (MS) 
             - Myasthenia Gravis (MG)
        C) Dermatological Diseases:
            - Different clinical forms of Pemphigus
            - Psoriasis
            - Vitiligo
2- Candidate gene studies to explore autoimmune diseases susceptibility genes.  
3- Determination of new auto-antigens by different techniques such as immuno-proteomics.  
4- Evaluation of new medicines in treatment of different autoimmune diseases.
5- Study the effects of herbal medicines on cellular components of immune system in different autoimmune diseases using in vitro experimental models.
6- Identification and determination of differents effective factors in different autoimmune diseases.
7- Candidate gene studies to explore autoimmune diseases susceptibility genes.
8- Immunotherapy of different autoimmune diseases by using biologic and non-biologic agents.

Autoimmune Diseases Research Center
Shiraz Medical School, karimkhan-zand Blvd. Shiraz 71345-3343, Iran.
Tel: +987112357181
Fax: +987112357181